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When continual LogMAR details had been offered we analyzed the visual acuity and diploma of modify as steady info. The main time of result assessment was at three many years' follow?up, with unique observe?up periods analyzed as reported.We applied typical methodological techniques expected by Cochrane. Two overview authors independently evaluated
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Placebo capsules ended up identical in composition and appearance into the capsules containing active drug but didn't contain drug substance. In the course of the in-lifetime percentage of the research (November 2003), the IDMC proposed discontinuing the two hundred-mg dose depending on a heightened frequency of musculoskeletal adverse consequences